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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a28ade9f8def8b60839c5f529af20b048703e58480b473a9a8f85dacb3f35de' 
  AND token = 'K2IjSZccawZ4xEMN5GHKXq4rnW/yJYITDp55AIwH9C8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}