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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ed72e4f64397c33bf82acc5e6e0871e95b030c7129d5d15d8a001b74d24191c' 
  AND token = 'LU+x3GN4ta8j4nQbAfupsQbvfQeSQ3ticRTXZOiHPpI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}