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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f2dc0bd9a2855be41356f577f62b7a1c902ec6ac36c6c9e81757ef062868f67' 
  AND token = 'E3VKpN1adXAx+UyUKAx+SttRkUaREGxKOBcnWHUdADY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}