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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ec281309c7e32a24125c046fa86070a33f54a1f1ba3fa5f3fe37ef9b5e5c635' 
  AND token = 'IzVLjbbxQrgwTw3OpIAn42ewfhA5KT2YNCAEAszugn8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}