SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b27a1b759506505b04e57c64b4fe4e25a967ac3b5f455ff95c38a6bc3398088' 
  AND token = 'PZYKiqe3bkktFUtd44/EGH2bU2QliGAYJV7mLtcV0CU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}