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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a748a680aaadfac6aa253c93e3106fe0a5ff5dbf3e5f9360cc7c33806ca3107f' 
  AND token = 'IHibj0o3NUXmWbaffGlly6UO8Ysa1wNKC8ITP3K5fnc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}