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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54d879e5d726ba57ead9d2e9fda4ad4036960934b16cfe3f2f364057cb375319' 
  AND token = 'RwSOSfi+fYwHtEsycdk+CKvNh7X3eDfBWxMNvHsFotY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}