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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '636146a596584f7e44fca73ab620256284d5005054d5a816a54c1c5494c9f50b' 
  AND token = '1VayB9SbbDaffjzUt+twddbz4pZBuDPmp9xINw2Ifso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00121

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}