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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '724dc680568e9a04bea9220bae287aa23a6e0db98a4b2fe9b2f2bad24be044d6' 
  AND token = 'pA8lB/6zjAMq+hQ+hW9m+n+zkorYV1EA2EdRl4QEXGM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}