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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b35c92d4074fde26d05a4865a072ac13deea9fa656d7a7a2411e51dafc86875' 
  AND token = 'IBU4oUaz0S2jhYtl+MAhHV2SB4S44qj9dd1yTGO0Lyw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}