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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11576039e09ce51e0eb90f246e295fdd1ac20707385a41c47b5ea8be98a705d2' 
  AND token = 'Li5YZc5oU1/n7TkdnNp+hO57D+xvEbg5kN7eM9zJAqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}