SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b81f9400f1c12a612335b9ff83076be5476f15516bfb1a54379a6c3f7616579b' 
  AND token = '66DJSPuvca1gjoJl7Ezs2DpoO0UpIAnjJCPzgfZ7+0o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}