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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '163f94489da10346b2060ae7fc33f62e1b47f1a1eb16bfd396a0fbcd3453812d' 
  AND token = 'X899CqEbx89gTfS5np20v2g7FBHVPMW6TZlU2OaS3MU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}