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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18f4c1ff44aafd3e6bde13960ebe28942c09a9b19139a6fe84056e486e71eea3' 
  AND token = 'vPL1FGp3X3K8zIBUCLT4RLlli8EjX6C9SCCckFIr6KQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}