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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25c089eb2a4eac0e40e324abb2a131e12888185079a4f72690dc07d82a25ea91' 
  AND token = 'hdyMeJvYJ5PcLPRGe+zzNLIitSnIFN6ZDhSjrvFhVTQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}