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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80129922faa31413c56f4bcf321648acc67fb1a02043e7f96ef4407918414f09' 
  AND token = 'QkR2GJ+b2vsmWqLKK61T0jfdS7ao0klvIYStQ5XPYtM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}