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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fedadf7965b086817c0ed9b799202d4e9f5a163f35ea5a26db228dc9056953d7' 
  AND token = 'pU13P8Dv2PvE4kv9/rQj0D9KgwQVwCfE0D1DZHQTlXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}