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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab97b5eb056199379414274614d63143df6ed5bdc7a522c292551d591dd02cb3' 
  AND token = 'De7DLl/4A0u5yswJ5XVofE//Tnx8aHLrOJWRc7GDxG4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}