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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f3ed9667317b53a8ce8803c4dad09811a7072aba378a0a131b698719a1e1727' 
  AND token = 'l49wYKjk9oFm7ETJOBogzeeiZur3XW+kVhvS8YqySk0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}