SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd08ad2244476f5a7a445980feb8c1b79fbff36805781027fdf94ff4c2e5a43ab' 
  AND token = 'WCtIfkYBSkV1Ot72CsxSrrcXvbnzYcU5ivzbjSgpz/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}