SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '717ded0b5043789fa4fd4eacc171e4f5365821af996a97e29f655cac0e283e43' 
  AND token = '7u1cbBkZVCNbEx+GliLQjPLKpkIcia7PpY4YdnjJu4U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}