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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '494d9cde5727d02d23e291726d3447a6091bd8f5dce0f1a0e75def4c8b7f7baa' 
  AND token = 'Kh6pW1byP5T1soKMQJtKbCWdhKNVIRf0bzijQOfbgq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}