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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '794d33b5024cfadcc04a88899441c18c824c9a0417b0f6da74796b65a74cf822' 
  AND token = 'HNSX3In3N6Ida3LSoKyeoLRkysvobIoHNBgtOIT+ooo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}