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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81b00422ddaf54e20c7e88c8c46eed9da0d5ef042b130532fb775bfd13b1fa17' 
  AND token = '+PkkXctdWXB008ClKkzxGXCK9sTk/K/grqQxKS4iX9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}