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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ac5758499a99ef0b7fbefb34f51ebee880491eefdfdc5b3c04caa456de4858a' 
  AND token = 'fZwQk0Rmw5gz7iaVM+mW7rKNe2szw7EtkGTo5w66SZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}