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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f52fc00d8791c3cf9c78e5d1b47e9005e827207ee9302327f2eb58b8e89498a' 
  AND token = 'xGTHrln+WdwmdkchN80FPDdhYrDq3ns3iENsd2cpJL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}