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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd9018776d0c12d789e58988d21ebd2571bfb05b70d5f6a292b44eed4983ce0c' 
  AND token = 'kv1mwMa2zfwmIZ+c9ZrnF18zdQyASA3ZdEb1DO5yees=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}