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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd42285d9da338847a93ea5aec90fc1ae68e5519e742b3149af6431d235f50c47' 
  AND token = 'dtjgVuqtDaLP9LNXri2bo0wEXUWIEb8jFRKs+t9AfAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}