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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8b4fe604e54b88f6d0e285c16ab858e9e0643de1f33e27c83b9baaabe45b270' 
  AND token = 'SRcbZWM6OKxEYeKa8Y5d3lSMINdDo4ohaCdd5DOT0aY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}