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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86642701cb81a55b67155d25111b2476417a9f9e8678af6077c140a215b832e0' 
  AND token = 'd0m2ZmXiof+fplgfxQSkG67FTgR6eR6HnFxagyYPWzk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}