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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8e878e0b3c67b045c9478fb7cee3a6f0b1325886d905306090e4e0fea69728d' 
  AND token = 'Tsq3Jx2xUjIJpiuEiMMYTXKoqu09C0AqrH+oCOkr284=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}