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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a12cde5fd0ef42e8e8b4fd3c53c009d7a47859a0b72c972817f75f94194f687' 
  AND token = 'boqr/oA1YUvnD5PLsRK76fCykuTh4NdkhbMNUXbGGmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}