SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c60ece8fc9f3e393aa1add2c73d85b6e18550181ba74559353df0c14ee30b2e1' 
  AND token = '2PsAQDrYKG63gZ6cKKVGaG2m5CgTphT7SW9YlSQeZ+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}