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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7728f3337e49bcd6c3ad34be8ea9c35c54277f00d7a2325e755691b50b291d75' 
  AND token = 'DaihRlyxhxqh7k2GJNO5aRy8abkgrgXIM3PTpFqZaNQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}