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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa09ca06208d595072eb78ac9af0d91533330f378a4236a55a2845b2a672c7bf' 
  AND token = 'ZlTxAkFAckEoZdM84DFDxubPRhujPHm5CDa0/wa2Aps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}