SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3773f6ee161427def3def59025e379167e673f29d684bfd354b0c55436720859' 
  AND token = 'BJ27lXeRn9XN6pAFdFfeHEbQpM258r3bsLE6jo+EXj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}