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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '106b6fcb61107a3f836606155cf2339dbf847a7b455e0463daa56bff1d1cd850' 
  AND token = 'jGl5DC30SPT5tIwIW+ppsfCYyMLe7yDmaGTOl8NuaKg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}