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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1daa43a0af28db0e958cdc1ad73f2d2c80a485b7dd86078a46f4177288a5b76' 
  AND token = 'wI0MYupSV+dz4iA+HZL5MbST5vrA6cdTZKJsZuOn0eU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}