SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65ac23407a512f1e41a3c661ff0ac5fd58db46b3a938146987929ee12144f2cd' 
  AND token = '1/trqoRkkNc9M7TlNxGKD1QcRiPF96y52iaK8pf5mvY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00075

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}