SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c77fc047eb216444757fad2ad27c03a644d83dfc141f0d1b2734e6e9280af55' 
  AND token = '9MbaLuxQ7NfjhmVe0f0CWpFYl3hHDYWhAwqqrA9soaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}