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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3f606dea1adc4c0e64c790b7ee41bffac55a83d27a0ddead1f70f0fbf851896' 
  AND token = 'MbWGJH/Phgtdh3M19pVzMWjr+c1ewQx1G+qY/+nMgFA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}