SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '02ed5b25b70d215a26cfd76e11cf349133ccca74891bbf75d60b34f28a0e387c' 
  AND token = 'f4xxUO1GTbKrh7+6jGOcb25oVYY3aF9rxmJf3tzQttY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}