SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4276a19d47011c231434f1c68551d3626da31df7ac2e3dd6e6b3a36cbb7ac1d3' 
  AND token = 'ftUkY282s2dqJTr+PmV6l9F5Ebh4SA4CSI/UDD/EqbY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}