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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8748d23cb8ec257a00fe864e3753d2abd3d033b90259f8348c67e680c4cb1a90' 
  AND token = 'yB/bE6FwB2GIwZfDa8tCmFeJ5qJnYOmrsAV4txAEsF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}