SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ba1d25419fa2b464055e6a7d91811d8ee0bd8839b7292627ec14cda1204a99a3' 
  AND token = 'YXheZx/TEs/FruBp27NntHuNqtQTCbdTvI1+zLLQQaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}