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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b20fc9bd629fa82fec10f12807de92dcc7d53e2cab46dcb433a1b7bd66dd860' 
  AND token = '9VRPbXnWv3qMDj0NDG6Qy87N9XCHYSWRQwcE1Ntj4tg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}