SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59b5ac671104ff76bee63a9b47d78ed939d1d7b9c39d0cc180c82af2ef9fc504' 
  AND token = 'G1H0OyMGXZ+STLWjn8+5O/WPZX/Z6ysojIEgzvsc3kU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}