SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58b1258030d9caa996f62056f9f0f601f1178f87a53ebf80f2a66ad536620f22' 
  AND token = '/MvIoZ1QYtgeaUMYJGjqDYRVbGTpE6vtnIOOJUUi36A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}