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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4142d46081ff2dd8c2b3533ea9cc8d8fd6a7555b1b74267fd40e0d00498ff231' 
  AND token = 'YhakxIAQf2UQkHLWagi1Rz6bb0yU+gKwTc/6dCKlS1w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}