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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5dcd28418c69eeeff04396604e4fde62f7e91fe167410cb2c750626c3bcda2ca' 
  AND token = '3N4ld2zCZiL0W9AF+y4YzLtGTG3WgSvyp4Ar5VE9Njk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}